Title of article
Differential production of interleukin-6 and its close relation to liver metastasis in clones from murine P815 mastocytoma
Author/Authors
Hojo، نويسنده , , Hiroshi and Sun، نويسنده , , Rongjin and Ono، نويسنده , , Yuki and Shishido، نويسنده , , Takao and Obara، نويسنده , , Emiko and Yamazoe، نويسنده , , Yasushi H. Hashimoto، نويسنده , , Yoshiyuki، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
5
From page
55
To page
59
Abstract
Interleukin-6 (IL-6)-producing abilities of plastic-adherent and plastic-non-adherent P815 clones were investigated in connection with the liver metastasis. Most adherent clones produced IL-6 at high level (over 10 ng/105 cells per 48 h), and they coincided with highly liver-metastatic clones. The remaining adherent and all the non-adherent clones tested produced IL-6 at low level (under 1.5 ng/105 cells), and they coincided with the low or non-liver-metastatic clones. The IL-6 production was greatly enhanced by IL-1α, but not by IL-6, tumor necrosis factor-α or interferon-γ.
Keywords
P815 mastocytoma , Liver metastasis , Clone , Interleukin 6
Journal title
Cancer Letters
Serial Year
1996
Journal title
Cancer Letters
Record number
1797556
Link To Document