Title of article
Breast cancer prognostic significance of some modified urinary nucleosides
Author/Authors
Sasco، نويسنده , , Annie J. and Rey، نويسنده , , Françoise and Reynaud، نويسنده , , Cécile and Bobin، نويسنده , , Jean-Yves and Clavel، نويسنده , , Michel and Niveleau، نويسنده , , Alain، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
6
From page
157
To page
162
Abstract
The prognostic significance of six urinary modified nucleosides, 5-methylcytidine (5-MeCyd), 4-acetylcytidine (4-AcCyd), 1-methylinosine (1-MeIno), 1-methyladenosine (1-MeAdo), 7-methylguanosine (7-MeGua) and pseudouridine (Ψ-Urd) was evaluated in 68 breast cancer patients of the specialized cancer hospital of Lyon (France). Excretions of 1-MeIno and 1-MeAdo were significantly higher in patients hospitalized in the medical rather than surgical ward, reflecting more advanced disease, and also among patients who died within 5 years of follow-up as compared to those still alive. These results suggest an unfavourable prognostic significance of high urinary excretion of 1-MeIno and 1-MeAdo in breast cancer patients.
Keywords
modified nucleosides , Urinary excretion , Prognosis , breast cancer
Journal title
Cancer Letters
Serial Year
1996
Journal title
Cancer Letters
Record number
1797579
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