Title of article :
Inhibitory effect of caffeic acid phenethyl ester on human leukemia HL-60 cells
Author/Authors :
Chen، نويسنده , , Jian-Hong and Shao، نويسنده , , Yu and Huang، نويسنده , , Mou-Tuan and Chin، نويسنده , , Chee-Kok and Ho، نويسنده , , Chi-Tang، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1996
Abstract :
Caffeic acid phenethyl ester (CAPE) was synthesized from caffeic acid and phenethyl alcohol (ratio 1:5) at room temperature with dicyclohexyl carbodiimide (DCC) as a condensing reagent. The yield was about 38%. CAPE was found to arrest the growth of human leukemia HL-60 cells. It also inhibits DNA, RNA and protein synthesis in HL-60 cells with IC50 of 1.0 μM, 5.0 μM and 1.5 μM, respectively.
Keywords :
Caffeic acid phenethyl ester , HL-60 cells , antitumor , Propolis , Caffeic acid
Journal title :
Cancer Letters
Journal title :
Cancer Letters
