Title of article
trans,trans-2,4-Decadienal: cytotoxicity and effect on glutathione level in human erythroleukemia (HEL) cells
Author/Authors
Nappez، نويسنده , , C. and Battu، نويسنده , , S. and Beneytout، نويسنده , , J.L.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
5
From page
115
To page
119
Abstract
The effects of trans,trans-2,4-decadienal (DDE), an isomer of a lipid peroxidation product were investigated on the human erythroleukemia cell line (HEL TIB 180). DDE strongly inhibits cell growth and affects cell viability without any differentiating effects. DDE treatment of HEL cells leads to a marked variation of the cellular glutathione level (GSH) and is involved in the beginning of DNA fragmentation.
Keywords
HEL cells , Hydroxyalkenals , trans , trans-2 , glutathione , 4-Decadienal
Journal title
Cancer Letters
Serial Year
1996
Journal title
Cancer Letters
Record number
1797672
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