Author/Authors :
Haylett، نويسنده , , Ann K. and McNair، نويسنده , , Fiona I. and McGarvey، نويسنده , , David and Dodd، نويسنده , , Nicholas J.F. and Forbes، نويسنده , , Ethel and Truscott، نويسنده , , T.George and Moore، نويسنده , , James V.، نويسنده ,
Abstract :
The singlet oxygen quantum yields and superoxide quantum yields for a series of novel compounds based on an asymmetrical protoporphyrin molecule have been examined. Electron spin resonance was used to measure superoxide yield and time resolved luminescence for singlet oxygen. A comparison between these results and previously published cell survival data was carried out, A broad association was found between singlet oxygen quantum yield and clonogenic cell kill.
Keywords :
Asymmetrical novel photosensitizers , Clonogenic assay , Superoxide , singlet oxygen , photodynamic therapy
