Title of article
Serum concentration of hepatocyte growth factor in patients with metastatic breast cancer
Author/Authors
Maemura، نويسنده , , Michio and Iino، نويسنده , , Yuichi and Yokoe، نويسنده , , Takao and Horiguchi، نويسنده , , Jun and Takei، نويسنده , , Hiroyuki and Koibuchi، نويسنده , , Yukio and Horii، نويسنده , , Yoshio and Takeyoshi، نويسنده , , Izumi and Ohwada، نويسنده , , Susumu and Morishita، نويسنده , , Yasuo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
6
From page
215
To page
220
Abstract
The serum concentration of hepatocyte growth factor (HGF) was examined in 34 patients with metastatic breast cancer. Although no significant difference was observed between HGF concentration and the site of metastasis, serum HGF levels were slightly higher in patients with liver metastasis and in patients with multiple metastatic sites than in patients with other lesions. Significantly higher levels of serum HGF were observed in patients with progressive metastasis of breast cancer compared with those with stable metastasis. The patients with high HGF levels exhibited a significantly shorter survival rate than those with low HGF levels. Circulating HGF levels may be a useful indicator for the progression of metastatic lesions and the prognosis of patients with metastatic breast cancer.
Keywords
Malignant progression , breast cancer , Hepatocyte growth factor , metastasis
Journal title
Cancer Letters
Serial Year
1998
Journal title
Cancer Letters
Record number
1799501
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