Title of article
Difference in prognostic value between sialyl Lewisa and sialyl Lewisx antigens in blood samples obtained from the drainage veins of the colorectal tumors
Author/Authors
Nakagoe، نويسنده , , Tohru and Sawai، نويسنده , , Terumitsu and Tsuji، نويسنده , , Takashi and Jibiki، نويسنده , , Masa-aki and Ohbatake، نويسنده , , Masayuki and Nanashima، نويسنده , , Atsushi and Yamaguchi، نويسنده , , Hiroyuki and Kurosaki، نويسنده , , Nobuko and Yasutake، نويسنده , , Toru and Ayabe، نويسنده , , Hiroyoshi and Tagawa، نويسنده , , Yutaka، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
10
From page
159
To page
168
Abstract
Subtraction values, (i.e. values obtained by subtracting the serum titer of sialyl Lewisa (CA19-9) and sialyl Lewisx (SLX) antigens in peripheral venous blood from the serum titer of the same antigen in the tumorʹs drainage venous blood) were determined in order to clarify whether or not such values for these specific antigens (d-CA19-9 and d-SLX) are prognostic factors after resection for colorectal cancer. The blood samples were obtained from 144 colorectal cancer patients during surgical excisions of the tumors. Univariate and multivariate analyses revealed that d-SLX level was an independent prognostic factor, separate from stage, while d-CA19-9 level did not have any additional prognostic value. In conclusion, a high d-SLX level is a predictor of poor outcome after surgery.
Keywords
sialyl Lewisa , Sialyl Lewisx , Colorectal Cancer , Drainage vein
Journal title
Cancer Letters
Serial Year
2000
Journal title
Cancer Letters
Record number
1801844
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