Author/Authors :
Uenosono، نويسنده , , Yoshikazu and Natsugoe، نويسنده , , Shoji and Higashi، نويسنده , , Hiroshi and Ehi، نويسنده , , Katsuhiko and Miyazono، نويسنده , , Futoshi and Ishigami، نويسنده , , Sumiya and Hokita، نويسنده , , Shuichi and Aikou، نويسنده , , Takashi، نويسنده ,
Abstract :
The purpose of this study was to investigate the relationship between colloid size and the detection of sentinel nodes (SN) in early gastric cancer. Three size of 99mTechnetium–tin colloids (500, 100 and 50 nm) were preoperatively injected into the submucosa under endoscopic control. Lymph node metastasis and micrometastasis was examined. RI-uptake in the hottest nodes and the total RI-uptake in the hot nodes were highest in the size of 100 nm. At least one lymph node metastasis, including micrometastasis, was included in the hot nodes. RI-labeled colloid size was one of the important factors to detect SN in early gastric cancer.
Keywords :
Sentinel node navigation surgery , radioisotope , Lymph node metastasis , early gastric cancer , Micrometastasis