Author/Authors :
Nakagoe، نويسنده , , Tohru and Tsuji، نويسنده , , Takashi and Sawai، نويسنده , , Terumitsu and Tanaka، نويسنده , , Kenji and Hidaka، نويسنده , , Shigekazu and Shibasaki، نويسنده , , Shin-ichi and Nanashima، نويسنده , , Atsushi and Ohbatake، نويسنده , , Masayuki and Yamaguchi، نويسنده , , Hiroyuki and Yasutake، نويسنده , , Toru and Sugawara، نويسنده , , Kazuyuki and Inokuchi، نويسنده , , Naoko and Kamihira، نويسنده , , Shimeru Kamihira، نويسنده ,
Abstract :
Peri-operative serum levels of interleukin-6 (IL-6) were determined in 62 patients who underwent resection of colorectal cancer to clarify the relationship between nutritional status and IL-6 response. Patients were divided into two groups based on creatinine height index: malnourished group (n=13) and normally nourished group (n=49). The preoperative median serum level of IL-6 in the malnourished group was significantly higher than in the normally nourished group (P=0.041). The postoperative median serum level of IL-6 in the malnourished group also tended to be higher. In conclusion, the peri-operative IL-6 response may be activated in malnourished colorectal cancer patients.
