Author/Authors :
Alves، نويسنده , , Gilda and Menezes Trindade Macrini، نويسنده , , Camila and de Souza Nascimento، نويسنده , , Patrيcia and Carlos Morais، نويسنده , , José and Augusto Ornellas، نويسنده , , Antonio، نويسنده ,
Abstract :
Epstein-Barr Virus (EBV) is prevalent in all human populations and high titers of antibody correlate with specific malignancies such as Burkittʹs lymphoma, nasopharyngeal carcinoma, and Hodgkinʹs disease. Our study detected EBV DNA in 20 of 21 penile tumor samples using PCR reaction. Expression of EBV protein LMP-1 was identified in tumor cells from two EBV PCR-positive tumors. Our findings indicate that EBV can be implicated in rising and/or progression of penile tumors independently of the histological type.