Title of article
IgG antibodies to HPV16, 52, 58 and 6 L1-capsids and spontaneous regression of cervical intraepithelial neoplasia
Author/Authors
Matsumoto، نويسنده , , Koji and Yasugi، نويسنده , , Toshiharu and Oki، نويسنده , , Akinori and Fujii، نويسنده , , Takuma and Nagata، نويسنده , , Chisato and Sekiya، نويسنده , , Souei and Hoshiai، نويسنده , , Hiroshi and Taketani، نويسنده , , Yuji and Kanda، نويسنده , , Tadahito and Kawana، نويسنده , , Takashi and Yoshikawa، نويسنده , , Hiroyuki، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
5
From page
309
To page
313
Abstract
To identify the predictive markers for spontaneous regression of cervical intraepithelial neoplasia (CIN), we examined whether IgG antibody responses to common human papillomavirus (HPV) L1-capsids correlate with CIN regression. In a cohort study, a total of 116 Japanese women with CIN grade I/II were tested for cervical HPV DNA and serum IgG antibodies to HPV16/52/58/6 L1-capsids. Our data suggest that baseline IgG reactivities to HPV L1-capsids do not serve as a predictive marker of CIN regression, in contrast to histological CIN grades and HPV DNA status.
Keywords
L1-capsids , CIN , VLP , HPV , Regression
Journal title
Cancer Letters
Serial Year
2006
Journal title
Cancer Letters
Record number
1808807
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