Author/Authors :
Platet، نويسنده , , Nadine and Liu، نويسنده , , Shi Yong and Atifi، نويسنده , , Michèle El and Oliver، نويسنده , , Lisa and Vallette، نويسنده , , François M. and Berger، نويسنده , , François and Wion، نويسنده , , Didier، نويسنده ,
Abstract :
Under standard culture conditions, tumor cells are exposed to 20% O2, whereas the mean tumor oxygen levels within the tumor are much lower. We demonstrate, using low-passaged human tumor cell cultures established from glioma, that a reduction in the oxygen level in these cell cultures dramatically increases the percentage of CD133 expressing cells.
Keywords :
Cancer stem cell , Cell culture , Glioma , CD133
