Effects of the 6β-7β-epoxide of 12-O-tetradecanoyl-phorbol-13-acetate on radiation transformation in vitro

Experiments were performed to compare the abilities of 12-O-tetradecanoyl-phorbol-13-acetate (TPA), croton oil and TPA-6β-7β-epoxide to enhance radiation transformation in vitro. Both croton oil and TPA-6β-7β-epoxide were more powerful than TPA in the ability to promote radiation transformation in vitro.