Author/Authors :
Ansari، Roya نويسنده PHD Student of Animal Developmental Biology, Kharazmi University, Tehran, Iran Ansari, Roya , Sahinfard، Najmeh نويسنده Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran Sahinfard, Najmeh , Namjou، Abdolrasool نويسنده Pathology Department, Islamic Azad University of Shahrekord Branch, Shahrekord, Iran Namjou, Abdolrasool , Rafieian، Mortaza نويسنده Isfahan Governer Office, Isfahan, Iran Rafieian, Mortaza , Shirzad، Hedayatollah نويسنده Department of Immonology, Medical Plants Research Center, Shahr-e-Kord University of Medical Sciences, Shahr-e-Kord, Iran Shirzad, Hedayatollah , Rafieian-kopaei، Mahmoud نويسنده Department of Pharmacology, Medical Plants Research Center, Shahr-e-kord University of Medical Sciences, Shahr-e-Kord, Iran Rafieian-kopaei, Mahmoud
Abstract :
Introduction: Traditionally, burn wound healing activities have been claimed for Teucrium polium. Teucrium polium possesses antioxidant and inflammatory activities and seems to ameliorate burn wound healing. This study was performed to evaluate the effects of Teucrium polium on burn healing in Balb/C mice.
Materials and Methods: In this preclinical experimental study 56 mice were randomly designated into 4 equal groups. Burn wounds were made using a hot plate with a surface area of 1.5 cm2. Animals were treated with Teucrium 2%, Silver sulfadiazine or Vaseline 2 times per day for 21 days. The forth group received no treatment.
Results: The percentage of burn wounds healing and total time required for complete healing were evaluated and compared in different groups. Data were analyzed using ANOVA test.
Conclusion: Teucrium extract accelerated the burn wound healing more rapidly than control groups (p < 0.01). Teucrium polium is effective on burn wounds healing and might be beneficial in these groups of patients.