Author/Authors :
Mehrvarzfar، Payman نويسنده Department of Endodontics, Dental Branch, Islamic Azad University, Tehran, Iran , , Pourhashemi، Anahita نويسنده Department of Restorative Dentistry, Dental School, Shahid Beheshti University of Medical Science, Tehran, Iran , , Khodaei ، Fatemeh نويسنده Endodontist, Tehran-Iran. , , Bohlouli، Behnam نويسنده Department of Oral and Maxillofacial Surgery, Dental Branch, Islamic Azad University, Tehran, Iran; , , Sarkarat، Farzin نويسنده Department of Oral and Maxillofacial Surgery, Dental Branch, Islamic Azad University, Tehran, Iran , , Kalantar Motamedi، Mojdeh نويسنده Private Practice, Tehran, Iran , , Layegh Nejad، Mohammad Karim نويسنده Department of Endodontics, Dental School, Shahid Beheshti University of Medical Science, Tehran ,Iran ,
Abstract :
Introduction: Deep and long-lasting anesthesia is essential throughout endodontic treatment. This
study was conducted to compare the effect of adding fentanyl to epinephrine-containing lidocaine
on depth and duration of local anesthesia in painful maxillary molars with irreversible pulpitis
(IRP). Methods and Materials: This randomized double-blind, clinical trial with parallel design
was conducted on 61 healthy volunteers; the control group received a mixture of normal saline and
2% lidocaine with 1:80000 epinephrine and the experimental group received a mixture of fentanyl
and 2% lidocaine with 1:80000 epinephrine. The depth and duration of pulpal anesthesia were
evaluated by means of electric pulp testing in 5-min intervals during a period of 60 min. Pain
intensity was recorded five times: before injection, after injection, during access cavity preparation,
initial file placement and pulpectomy using visual analog scale (VAS). All data were analyzed and
compared using the chi-square and Mann-Whitney tests. Results: Except for one patient in the
control group, all others had deep and long-lasting anesthesia. The difference between pain
intensity of the control and experimental groups was not statistically significant (P > 0.05).
Conclusion: Addition of fentanyl to conventional local anesthetic solution did not increase the
effectiveness of infiltration in patients diagnosed with IRP.
