Title of article
Clinical significance of lymph node micrometastasis of pN0 esophageal squamous cell carcinoma
Author/Authors
Matsumoto، نويسنده , , Masataka and Natsugoe، نويسنده , , Shoji and Nakashima، نويسنده , , Saburo and Sakamoto، نويسنده , , Fuminori and Okumura، نويسنده , , Hiroshi and Sakita، نويسنده , , Hironori and Baba، نويسنده , , Masamichi and Takao، نويسنده , , Sonshin and Aikou، نويسنده , , Takashi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
9
From page
189
To page
197
Abstract
The lymph nodes of 59 patients with pN0 esophageal squamous cell carcinomas were examined immunohistochemically using cytokeratin (CK) antibody. Primary tumors were immunostained with cyclin D1 (CD1) and E-cadherin (E-cad) antibody. Lymph node micrometastasis (MM) was found in 39 (55.5%) patients. Tumor recurrence was found in 17 patients and all but one of them had MM. The 5-year survival rate was significantly poorer in patients with MM than in those without MM. Almost all patients with positive CD1 and negative E-cad expression had MM. The examination of CD1 and E-cad expression in primary tumors may be useful for predicting MM.
Keywords
Lymph node micrometastasis , Cytokeratin , immunohistochemistry , Postoperative recurrence , Esophageal squamous cell carcinoma
Journal title
Cancer Letters
Serial Year
2000
Journal title
Cancer Letters
Record number
1817123
Link To Document