Title of article
First report of t(8;21)(q22;q22) in a case of de novo acute monoblastic leukemia
Author/Authors
Christina Cox-Froncillo، نويسنده , , M. and Genuardi، نويسنده , , Maurizio and Bajer، نويسنده , , Jolanta and Livdi، نويسنده , , Esther and Adorno، نويسنده , , Gaspare and Venditti، نويسنده , , Adriano and Masi، نويسنده , , Mario and Giudiceandrea، نويسنده , , Paolo and Neri، نويسنده , , Giovanni and Papa، نويسنده , , Giuseppe، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1995
Pages
4
From page
82
To page
85
Abstract
Here we describe the case of a 30-year-old man with a diagnosis of de novo acute monoblastic leukemia (FAB M5a), whose karyotype analysis revealed the presence of the translocation (8;21)(q22;q22) as the sole chromosome anomaly. In spite of the rather good prognosis patients suffering from acute leukemia and carrying this translocation are supposed to have, our patient had a very poor outcome, including an early relapse resistant to any treatment and meningeal localization. Death occurred within 5 months from diagnosis. To our knowledge this is the first report of t(8;21)(q22;q22) in de novo acute monoblastic leukemia.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
1995
Journal title
Cancer Genetics and Cytogenetics
Record number
1817296
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