Author/Authors :
Nakagawa، نويسنده , , Masashi and Sugiyama، نويسنده , , Haruo and Ogawa، نويسنده , , Hiroyasu and Tone، نويسنده , , Shirou and Morishita، نويسنده , , Hiroshi and Ikeda، نويسنده , , Hiroshi and Aozasa، نويسنده , , Katsuyuki and Taniwaki، نويسنده , , Masafumi and Abe، نويسنده , , Tatsuo and Kishimoto، نويسنده , , Tadamitsu، نويسنده ,
Abstract :
Chromosome translocations involving various chromosome sites, including the sites of immunoglobulin loci (14q32,2p12,22q11) represent recurrent aberration in non-Hodgkin lymphoma (NHL). We report a novel case of intermediate lymphocytic lymphoma (ILL) with both t(14;19)(q32.3;q13.1) and t(3;22)(q27;q11.2). The t(14;19)(q32.3;q13.1) and t(3;22) (q27;q11.2) may represent reciprocal recombinations between immunoglobulin (Ig) H chain gene (14q32.3) and bcl-3(19q13.1) and between Ig λ chain gene (22q11.2) and bcl-6 (3q27), respectively.