Cytogenetic analysis of dedifferentiated chondrosarcoma

Cytogenetic analysis of a dedifferentiated chondrosarcoma with a fibrosarcomatous component revealed the following chromosomal complement: 47,XX,i(1)(q10),add(6)(q13),+7,+8,t(10;22) (p11.2;q11.2),+14,−15,−17,add(19)(q13.4). Chromosome studies of dedifferentiated chondrosarcoma are sparse. Three of the anomalies in the present study are similar to those previously described in dedifferentiated chondrosarcoma.