Title of article
Clinical and cytogenetic studies of two cases of Klinefelter syndrome with hereditary retinoblastoma and rhabdomyosarcoma
Author/Authors
O?ur، نويسنده , , G. and Sengun، نويسنده , , Z. and Arel-Kiliç، نويسنده , , G. and De Busscher، نويسنده , , C. and Ba?aran، نويسنده , , Ayda S. Agar Ozbek، نويسنده , , U. and Ayan، نويسنده , , I. and Sariban، نويسنده , , E. and Vamos، نويسنده , , E.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1996
Pages
5
From page
77
To page
81
Abstract
Two children with Klinefelter syndrome (KS), one associated with bilateral hereditary retinoblastoma (RB) and the other with rhabdomyosarcoma (RMS) are reported. Both were boys and chromosomally momosaic for KS. The hereditary retinoblastoma case yielded 46,XY,del(13)(q12q14.2)/47, XXYc,del(13)(q12q14.2) in PHA-stimulated lymphocytes. The rhabdomyosarcoma case yielded 46,XY/47,XXYc in peripheral blood cells whereas tumor revealed trisomy 8, trisomy 7, and t(7;13)(q33;q32) in addition to 46,XY/47,XXYc mosaicism.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
1996
Journal title
Cancer Genetics and Cytogenetics
Record number
1818926
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