Author/Authors :
Dhar، نويسنده , , Pawan Kumar and Devi، نويسنده , , Sulochna and Ramesh Rao، نويسنده , , T. and Kumari، نويسنده , , Usha A. Joseph، نويسنده , , Anita and Kumar، نويسنده , , M.R. and Nayak، نويسنده , , Satish and Shreemati، نويسنده , , Y. and Bhat، نويسنده , , S.M. and Bhat، نويسنده , , K.R.، نويسنده ,
Abstract :
Very few studies report the analysis of sister chromatid exchanges in ovarian cancer patients. We tested the null hypothesis that SCE frequency increases with the advancing stages of ovarian cancer and follows a Poisson distribution. As controls we examined age- and sex-matched healthy volunteers who had no such past history. An increased average SCE frequency was observed in ovarian cancer patients (6.34 ± 0.09) vis-à-vis controls (4.47 ± 0.12). Further, the data also suggested a stage-wise increase in the SCE frequency.
