Author/Authors :
Dierlamm، نويسنده , , Judith and Michaux، نويسنده , , Lucienne and Krِger، نويسنده , , Nikolaus and Wlodarska، نويسنده , , Iwona and Martiat، نويسنده , , Philippe and Zeller، نويسنده , , Wolfgang and Seeger، نويسنده , , Doris and Mecucci، نويسنده , , Cristina and Van den Berghe، نويسنده , , Herman and Hossfeld، نويسنده , , Dieter Kurt، نويسنده ,
Abstract :
We report on two cases, one with acute lymphoblastic leukemia and a second with lymphatic blastic phase of Philadelphia chromosome-positive chronic myelogenous leukemia, cytogenetically characterized by ider(9)(q10)t(9;22)(q34;q11).
ndings and the data of the 4 cases previously published indicate that ider(9)(q10)t(9;22)(q34;q11) represents a rare but recurrent chromosomal abnormality occurring in hematological malignancies with lymphoid differentiation, namely acute lymphoblastic leukemia and lymphatic blastic phase of chronic myelogenous leukemia, and most likely evolves from a preexistent der(9) involved in the standard t(9;22).
