Author/Authors :
Sainati، نويسنده , , L and Bolcato، نويسنده , , S and Montaldi، نويسنده , , A and Celli، نويسنده , , P and Stella، نويسنده , , M and Leszl، نويسنده , , A and Silvestro، نويسنده , , L and Perilongo، نويسنده , , Luca Cordero di Montezemolo، نويسنده , , L.Cordero and Basso، نويسنده , , G، نويسنده ,
Abstract :
A cytogenetic analysis was performed on short-term cultures of 43 previously untreated childhood central nervous system neoplasms of various histology. The cells were obtained from pediatric patients, none of whom had received therapy before karyotypic evaluation. Successful chromosome studies were performed on 24 tumors. The most commonly detected structural abnormalities involved chromosomes 1 and 17. Other structural chromosome abnormalities involved chromosomes 3, 6, 8, 9, 11, 12, and 20.