Author/Authors :
Neuhaus، نويسنده , , Christine and Dijkhuizen، نويسنده , , T. and van den Berg، نويسنده , , E. and Stِrkel، نويسنده , , S. and Stِckle، نويسنده , , M. and Mensch، نويسنده , , B. and Huber، نويسنده , , C. and Decker، نويسنده , , H.-J.، نويسنده ,
Abstract :
Renal oncocytomas comprise a cytogenetically heterogeneous group of tumors consisting potentially of cytogenetic distinguishable subgroups. Review of the literature revealed loss of chromosome 1 and Y as a possible anomaly for at least one subset of oncocytomas. The frequent finding of rearrangements involving chromosome 11 band q13 characterizes another subset of oncocytomas. We report the cytogenetic and pathological features of a renal oncocytoma diagnosed in a 72-year-old woman and found a t(9;11)(p23;q13) as a consistent abnormality. This supports the idea that translocations involving 11q13 define a further subset of oncocytoma.
