Author/Authors :
Solé، نويسنده , , Francesc and de Pablos، نويسنده , , JoséMarيa and Woessner، نويسنده , , Soledad and del Mar Pérez، نويسنده , , Maria and Jurado، نويسنده , , Manuel and Espinet، نويسنده , , Blanca and Grao، نويسنده , , Pilar and Moratalla، نويسنده , , Antonio and Esquivias، نويسنده , , Javier، نويسنده ,
Abstract :
We present a case of myeloid metaplasia with myelofibrosis (MM/MF), with tetrasomy 8 as the sole cytogenetic abnormality detected by conventional cytogenetic studies. Tetrasomy 8 was also detected by in situ interphase studies and confirmed by chromosome painting in metaphase. To our knowledge, this is the first case of MM/MF with tetrasomy 8. Noteworthy is the association with neurofibromatosis.
