Author/Authors :
Boavida، نويسنده , , M.G. and Ambrَsio، نويسنده , , P. and Dhermy، نويسنده , , D. and Silva، نويسنده , , C. and Correia Jr.، نويسنده , , M.E.، نويسنده ,
Abstract :
Trisomy 14 in hematologic disease is a rare finding and is almost exclusively associated with myeloid cell lineage. We present a case of refractory anemia (MDS-RA) with the uncommon features of marked elliptocytosis and schistocytosis in the peripheral blood and isochromosome 14q. The analysis of the clinical outcome of this case and of others of myelodysplastic (MDS)Imyeloproliferative syndromes with trisomy 14 as the sole abnormality suggests that it does not confer an unfavorable prognosis.