Author/Authors :
Pernice، نويسنده , , Francesco and Musolino، نويسنده , , Caterina and Mazza، نويسنده , , Giuseppa and Puglisi، نويسنده , , Domenico and Squadrito، نويسنده , , Giovanni and Frisina، نويسنده , , Nicola and Squadrito، نويسنده , , Giuseppe، نويسنده ,
Abstract :
We report a case of acute monoblastic leukemia [French-American-British (FAB) M5a] observed in a 38-year-old man and associated at diagnosis with a t(5;10)(q13;q26) found in cells from a bone marrow culture. The patient survived only 2 months after diagnosis. t(5;10) as a solitary chromosome abnormality has not been previously reported in M5a, and, in the case that we describe, it appears to be correlated with a poor prognosis.
