Author/Authors :
Shekhter-Levin، نويسنده , , Sofia and Ball، نويسنده , , Edward and Swerdlow، نويسنده , , Steven H and Li، نويسنده , , W.Victoria and Kapadia، نويسنده , , Silloo B and Sherer، نويسنده , , Maureen E. and Wald، نويسنده , , Niel and Gollin، نويسنده , , Susanne M، نويسنده ,
Abstract :
We present the case of a 40-year-old man with aggressive systemic mast cell disease. The patient had a predominant near-haploid clone in his bone marrow cells, detected by cytogenetic analysis performed at the time of diagnosis. The similarities between this case and a previously published case of near-haploidy in a patient with malignant mastocytosis suggest that near-haploidy may be a characteristic of aggressive systemic mast cell disease rather than an incidental finding.