Author/Authors :
Kubonishi، نويسنده , , Ichiro and Seto، نويسنده , , Masao and Murata، نويسنده , , Naoaki and Kamioka، نويسنده , , Mikio and Taguchi، نويسنده , , Hirokuni and Miyoshi، نويسنده , , Iaso، نويسنده ,
Abstract :
A male patient with a secondary acute monocytic leukemia whose leukemia cells had a t(10;11)(p13;q13) chromosomal abnormality is described. Gene analysis disclosed that the patient’s leukemia cells had MLL gene rearrangement. His leukemia cells responded poorly to chemotherapy, and the patient developed an unusual aggressive leukemia cutis. A t(10;11)(p13;q13) chromosomal abnormality that expresses MLL gene rearrangement has not been reported previously in secondary leukemia.
