Title of article :
Did the Four Human Cancer Cell Lines DLD-1, HCT-15, HCT-8, and HRT-18 Originate from One and the Same Patient?
Author/Authors :
Vermeulen، نويسنده , , Stefan J. and Chen، نويسنده , , T.R. and Speleman، نويسنده , , Frank and Nollet، نويسنده , , Friedel and Van Roy، نويسنده , , Frans M. and Mareel، نويسنده , , Marc M.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
Four human colon cancer cell lines, HCT-8, HRT-18, DLD-1, and HCT-15, with an epithelioid morphotype reproducibly formed α-catenin-deficient round cells. Using DNA fingerprinting, we found that these four cell lines have an identical genetic background. Our finding strongly suggests a genetic background for the reproducible loss of α-catenin and the ensuing acquisition of invasiveness in all four cell lines.
Journal title :
Cancer Genetics and Cytogenetics
Journal title :
Cancer Genetics and Cytogenetics
