Author/Authors :
Solé، نويسنده , , Francesc and Woessner، نويسنده , , Soledad and Florensa، نويسنده , , Lourdes and Espinet، نويسنده , , Blanca and Lloveras، نويسنده , , Elisabet and Pedro، نويسنده , , Carme and Besses، نويسنده , , Carles and Sabrafen، نويسنده , , Jordi Sans، نويسنده ,
Abstract :
We studied five cases of hairy cell leukemia (HCL) using conventional cytogenetics. All patients were diagnosed with typical HCL. Chromosome analysis was carried out on a 72-hour culture of peripheral blood. Phytohemagglutinin (PHA) mitogen was used. Clonal chromosome abnormalities were found in 2/5 patients (40%), a complex abnormality being identified in one of them. The chromosomes involved were: 1, 6, 7, 8, and 17. No patient showed trisomy 12 or a 14q+. An interesting result was the finding of del(7)(q32) as a sole anomaly.
