Author/Authors :
Yves Gancberg، نويسنده , , David and Kentos، نويسنده , , Alain and Dargent، نويسنده , , Jean-Louis and Roufosse، نويسنده , , Candice and Dzota، نويسنده , , Guy and Capel، نويسنده , , Paul and Feremans، نويسنده , , Walter and Verhest، نويسنده , , Alain، نويسنده ,
Abstract :
Numerous chromosome abnormalities have been described in myelodysplastic syndromes, but single karyotypic aberrations are much less frequent. We report the case of a 65-year-old woman who presented a trisomy 21 as the sole karyotypic anomaly for a refractory anemia with ring sideroblasts. The nature of such an anomaly is discussed in regard to pathogenesis and prognosis.