Author/Authors :
Go، نويسنده , , Yoshinori and Ohjimi، نويسنده , , Yuko and Iwasaki، نويسنده , , Hiroshi and Oka، نويسنده , , Kazunari and Ishiguro، نويسنده , , Masako and Kaneko، نويسنده , , Yasuhiko and Tsuchimochi، نويسنده , , Hitoshi and Tomonaga، نويسنده , , Masamichi and Kikuchi، نويسنده , , Masahiro، نويسنده ,
Abstract :
We report the results of cytogenetic analyses of three cases of meningiomas. The first case, a papillary meningioma, showed only one cytogenetic abnormality, 46,XX,t(1;4)(q44;q21). In contrast, the other two benign fibroblastic meningiomas showed loss of chromosome 22. Loss and/or rearrangement of chromosomes other than chromosome 22 appears to be associated with a more aggressive clinical course. It is suggested that a sole cytogenetic abnormality with a normal chromosome 22 indicates an atypical nature of meningioma.
