Title of article
Trisomy/ Tetrasomy of Chromosome 8 and +i(8q) as the Sole Chromosome Abnormality in Three Adult Patients with Myelomonocytic Leukemia
Author/Authors
Ferro، نويسنده , , M.T and V?zquez-Mazariego، نويسنده , , Y and Ramiro، نويسنده , , S and Santiago، نويسنده , , M.F and Garc??a-Sagredo، نويسنده , , J.M and Nu?ez، نويسنده , , R and Hern?ndez، نويسنده , , J.M. Ruiz-Roman، نويسنده , , C.San، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
3
From page
163
To page
165
Abstract
We report three cases of tetrasomy 8 associated with myeloid disease. Two patients had chronic myelomonocytic leukemia (CMMoL) and the other had acute monocytic leukemia (AML M5 FAB). Two patients had trisomy/tetrasomy chromosome 8 as the sole abnormality. The other patient with CMMoL had two normal 8 chromosomes plus one isochromosome 8q; this is the first case of long arm chromosome 8 tetrasomy without short arm 8 monosomy. This cytogenetic finding suggests the importance of the genes located in the long arms of chromosome 8.
Journal title
Cancer Genetics and Cytogenetics
Serial Year
2000
Journal title
Cancer Genetics and Cytogenetics
Record number
1822951
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