Author/Authors :
Sawyer، نويسنده , , Jeffrey R. and Binz، نويسنده , , Regina Lichti and Gilliland، نويسنده , , John C. and Nicholas، نويسنده , , Richard W. and Thomas، نويسنده , , James R.، نويسنده ,
Abstract :
Recurring reciprocal translocations have been identified as the primary chromosome aberrations in a number of neoplasms. These aberrations are often closely associated with particular morphologic or phenotypic subtypes of tumors and in some cases have prognostic implications. We have identified a novel reciprocal t(10;17)(p11.2;q23) in a case of low-grade myxoid fibrosarcoma, which may prove to be a new tumor specific chromosome aberration.