Author/Authors :
Salido، نويسنده , , Marta and Solé، نويسنده , , Francesc and Espinet، نويسنده , , Blanca and Zamora، نويسنده , , Lurdes and Woessner، نويسنده , , Soledad and Florensa، نويسنده , , Lourdes، نويسنده ,
Abstract :
Chromosomal abnormalities in patients with large granular lymphocyte leukemia (LGLL) are rare. Herein we present a novel cytogenetic abnormality t(11;12)(q12;q11) in a patient with LGLL identified by cross-species color banding (RxFISH). The application of RxFISH allowed the rapid and easy identification of a chromosome rearrangement that was not recognized by conventional cytogenetics. Therefore, RxFISH is a suitable complement to, but not a replacement for, conventional cytogenetics.
