Author/Authors :
Salido، نويسنده , , Marta and Solé، نويسنده , , Francesc and Espinet، نويسنده , , Blanca and Fernلndez، نويسنده , , Cristalina and Zamora، نويسنده , , Lourdes and Woessner، نويسنده , , Soledad and Florensa، نويسنده , , Lourdes، نويسنده ,
Abstract :
Here, we report a 72-year-old male patient with acute myeloid leukemia (AML) without maturation. Cytogenetic study of a bone marrow culture revealed the following karyotype: 47,XX,+21,+i(21)(q10)×2. Fluorescence in situ hybridization study with a locus specific probe for 21q22 verified a pentasomy of 21q as a sole clonal cytogenetic abnormality. To our knowledge, this is the first report of pentasomy 21q in AML without Down syndrome.
