Author/Authors :
Specchia، نويسنده , , Giorgina and Albano، نويسنده , , Francesco and Anelli، نويسنده , , Luisa and Storlazzi، نويسنده , , Clelia Tiziana and Monaco، نويسنده , , Michele and Capalbo، نويسنده , , Silvana and Rocchi، نويسنده , , Mariano and Liso، نويسنده , , Vincenzo، نويسنده ,
Abstract :
Chronic lymphocytic leukemia (CLL) associated with myeloid antigens on the surface of B neoplastic cells is a recently identified immunologic variant confined to patients with CD5 negative B-CLL. We describe the case of a 61-year-old female diagnosed with CD5−, CD13+ B-CLL with a tetrasomy 3q revealed by fluorescence in situ hybridization analysis, in addition to trisomy 18. To our knowledge, this is the first reported case of B-CLL with this kind of cytogenetic abnormality.
