Author/Authors :
Amiel، نويسنده , , A. and Atzmon، نويسنده , , H. Michael Klein، نويسنده , , Z. and Kidron، نويسنده , , Moshe D. and Gaber، نويسنده , , E. and Vassilyev، نويسنده , , O. and Shalom-Paz، نويسنده , , E. and Fishman، نويسنده , , A. and Fejgin، نويسنده , , M.D.، نويسنده ,
Abstract :
Benign cystic teratoma, also known as dermoid cyst, is the most common of all ovarian neoplasms accounting for 10%–20% of all ovarian cysts. Most have a normal 46,XX karyotype. Less than 2% can undergo malignant transformation. By using the comparative genomic hybridization technique on nine benign ovarian cysts we were able to show two cases with chromosomal aberrations not seen before in dermoid cysts but known to be involved in malignant ovarian tumors. We speculate that these are the tumors carrying the potential for malignant transformation.
