Author/Authors :
Barbosa، نويسنده , , Miriam L. and Ribeiro، نويسنده , , Enilze M.S.F. and Silva، نويسنده , , Guaracira F. and Maciel، نويسنده , , Marcos E. and Lima، نويسنده , , Rubens S. and Cavalli، نويسنده , , Luciane R. and Cavalli، نويسنده , , Iglenir J.، نويسنده ,
Abstract :
The cytogenetic data on fibroadenomas and cystosarcoma phyllodes tumor of the breast, which are both biphasic breast tumors composed of epithelial and stromal components, are quite limited. In this study, we report on clonal chromosomal alterations in three fibroadenomas and one cystosarcoma phyllodes analyzed by GTG banding. The fibroadenomas presented mostly numerical abnormalities involving chromosomes 16, 18, and 21. One case presented a deletion on 17p. The cystosarcoma phyllodes presented numerous numerical abnormalities, mostly chromosome gains, and several marker chromosomes.
