Author/Authors :
Füzesi، نويسنده , , Lلszlَ and Frank، نويسنده , , Derk and Nguyen، نويسنده , , Christian and Ringert، نويسنده , , Rolf-Hermann and Bartels، نويسنده , , Henning and Gunawan، نويسنده , , Bastian، نويسنده ,
Abstract :
We performed cytogenetic analyses of 8 renal oncocytomas to identify chromosomal regions involved in the tumorigenesis of oncocytomas. All cases showed chromosomal findings corresponding to established cytogenetic subsets of renal oncocytomas: 3 cases with normal karyotypes, 1 case with rearrangement of 11q, and 4 cases with losses of chromosome 14. In the latter cytogenetic subgroup, monosomy 14 was additionally accompanied by either monosomy 1 in 2 cases or loss of 1p in a third case, providing insights in the cytogenetic evolution of this subgroup.
