Title of article :
MOLECULAR DOCKING STUDIES OF 2-MERCAPTO-5-(3-METHOXYPHENYL) 1, 3, 4 OXADIAZOLE THIONES WITH FOCAL ADHESION KINASE
Author/Authors :
Kiran، K.S. نويسنده Department of physics, Bangalore University, Bangalore, Karnataka, India , , Kokila، M.K. نويسنده Department of physics, Bangalore University, Bangalore, Karnataka, India , , R، Guruprasad نويسنده Scientific Director, Durga Femto Technologies & Research, Bangalore, Karnataka, India ,
Abstract :
The main objective of the present work is to perform molecular docking studies of the ligand 2-Mercapto-5-(3-Methoxy phenyl) 1,3,4 oxadiazole with protein focal adhesion kinase. A good correlation was observed in binding affinity of this complex. Using different inhibitors for this enzyme, it can be used as an anticancer therapy target.
