Author/Authors :
Tempescul، نويسنده , , Adrian and Guillerm، نويسنده , , Gaëlle and Douet-Guilbert، نويسنده , , Nathalie and Morel، نويسنده , , Frédéric and Le Bris، نويسنده , , Marie-Josée and De Braekeleer، نويسنده , , Marc، نويسنده ,
Abstract :
We report here two cases of patients with acute myeloblastic leukemia, type M1 (FAB classification), associated with a t(10;17)(p15;q21). Fluorescence in situ hybridization with the LSI PML/RARA dual-color probe showed the breakpoint to be distal to the RARA locus. Four other patients with this translocation have been reported, three of them having acute undifferentiated or poorly differentiated leukemia.
