Author/Authors :
Odish، نويسنده , , Omar Ferkad Faraj and Gotoh، نويسنده , , Akihiko and Liu، نويسنده , , Yi-Chang and Shoji، نويسنده , , Nohoko and Kimura، نويسنده , , Yukihiko and Kodama، نويسنده , , Atsushi and Ohyashiki، نويسنده , , Kazuma، نويسنده ,
Abstract :
We report a patient with myelodysplastic syndrome (refractory anemia) showing the karyotype 46,XY,+1,der(1;10)(q10;p10), resulting in trisomy 1q and monosomy 10q abnormality. This finding suggests that either trisomy of 1q or centromeric connection between chromosomes 1 and 10, rather than the absence of 10q, might be essential toward neoplastic transformation.
