Author/Authors :
Sipe، نويسنده , , J.C and Filippi، نويسنده , , M and Martino، نويسنده , , G and Furlan، نويسنده , , R and Rocca، نويسنده , , M.A and Rovaris، نويسنده , , M and Bergami، نويسنده , , A and Zyroff، نويسنده , , J and Scotti، نويسنده , , G and Comi، نويسنده , , G، نويسنده ,
Abstract :
A method for intracellular iron labeling of human mononuclear cells (lymphocytes and monocytes) for magnetic resonance imaging (MRI) using simple incubation of cells with approved MRI iron contrast agents is presented. Labeled cells can be detected by MRI in vitro, and this suggests the possibility that the technique could become a marker for in vivo lymphocyte and monocyte trafficking studies in acute inflammatory lesions such as those in Multiple Sclerosis.
Keywords :
Iron Labeling , Monocytes , MULTIPLE SCLEROSIS , Lymphocytes
