Proton MR spectroscopy of cerebellitis

Single voxel proton MR spectroscopy (1H-MRS) of the vermis was obtained in two patients with cerebellitis. In the acute phase 1H-MRS revealed low N-acetyl-aspartate (NAA)/creatine (Cr) and NAA/choline (Cho) and normal Cho/Cr ratios. Decrease of the concentration of NAA was confirmed by quantitative analysis in one patient. The NAA/Cr and NAA/Cho ratios and NAA concentration were increased in 1H-MRS examinations obtained 10 and 24 months after the acute episode. 1H-MRS demonstrates reversible metabolite changes in cerebellitis.