Radiothérapie des métastases vertébrales du cancer du sein. ہ propos dʹune série de 108 patientes

SummaryPurpose pective analysis of analgesic, decompressive and remineralization effects of radiation therapy for spinal metastases in breast cancer. ts and methods anuary 1990 to December 1992, 108 patients with breast cancer were treated by irradiation at the Bergonié Institute for a first spinal metastasis. Three patients had undergone previous surgery (laminectomy and Dovesʹ frame). The indication of radiation therapy was analgesic (102 patients) or decompressive (six patients). The usual irradiation scheme was 30 Gy / 10 fractions / 2 weeks. s algesic effect was considered as ‘complete’ or ‘almost complete’ (83%), ‘moderate’ (13%) or absent (4%). The mean time to the maximum analgesic response was 35 days. The duration of both the analgesic response and remineralization effects could not be retrospectively assessed due to lack of data. Decompressive effects were complete in five cases and absent in one case. A second spinal radiation therapy was necessary 78 times (eight times in junction field within 6 months following the first treatment). Spinal cord compression occurred either out of (three cases) or within (one case) the irradiated field. sion ion therapy for spinal metastases in breast cancer remains a palliative analgesic treatment. Indication for decompression is rare. However, assessment of compressive ‘risk’ leads to discussion of radiological staging (contribution of magnetic resonance imaging) and possible previous treatment (vertebroplasty or osteosynthesis).