A new way for the internal functionalization of dendrimers

The selective reaction of amines and hydrazides with only one Cl on each P(S)Cl2 or P(O)Cl2 end group of phosphorus dendrimers, followed by the grafting of hydroxybenzaldehyde on the remaining P–Cl functions, and the subsequent growing of the dendrimer from the aldehyde is described. Allyl and pyrene derivatives have been grafted in this way inside the dendrimers during their growing. This constitutes a new way for the internal functionalization of dendrimers.