Title of article
Chelation-controlled highly diastereoselective catalytic hydrogenation of γ-hydroxy-α-methylenecarboxylic acid esters
Author/Authors
Nagano، نويسنده , , Hajime and Yokota، نويسنده , , Misaki and Iwazaki، نويسنده , , Yukiko، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2004
Pages
3
From page
3035
To page
3037
Abstract
We report the catalytic hydrogenation of γ-hydroxy-α-methylenecarboxylic acid esters over Pd/C in the presence of 4 equiv of MgBr2 in tetrahydrofuran yielding predominantly the corresponding syn-γ-hydroxy-α-methylcarboxylic acid esters.
Keywords
Catalytic hydrogenation , Solvent effect , Acrylic acid esters , Chelation control , Lewis acid
Journal title
Tetrahedron Letters
Serial Year
2004
Journal title
Tetrahedron Letters
Record number
1841244
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