Title of article :
Chelation-controlled highly diastereoselective catalytic hydrogenation of γ-hydroxy-α-methylenecarboxylic acid esters
Author/Authors :
Nagano، نويسنده , , Hajime and Yokota، نويسنده , , Misaki and Iwazaki، نويسنده , , Yukiko، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
We report the catalytic hydrogenation of γ-hydroxy-α-methylenecarboxylic acid esters over Pd/C in the presence of 4 equiv of MgBr2 in tetrahydrofuran yielding predominantly the corresponding syn-γ-hydroxy-α-methylcarboxylic acid esters.
Keywords :
Catalytic hydrogenation , Solvent effect , Acrylic acid esters , Chelation control , Lewis acid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
