Title of article :
Stereoselective CrCl2-mediated condensation of aldehydes with functionalized 1,1,1-trichlorides: synthesis of trisubstituted (Z)-chloroolefins
Author/Authors :
Falck، نويسنده , , J.R. and Bandyopadhyay، نويسنده , , Anish and Barma، نويسنده , , D.K. and Shin، نويسنده , , Dong-Soo and Kundu، نويسنده , , Abhijit and Krishna Kishore، نويسنده , , R.V.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2004
Abstract :
The CrCl2-mediated condensation of aldehydes 1 with a variety of functionalized 1,1,1-trichlorides 2 affords trisubstituted chloroolefins 4 in excellent yields and generally high Z-stereoselectivity. The intermediate dichlorohydrin adducts 3 can be isolated in good yields under conditions of limited reagent and reduced temperature.
Keywords :
Chromium , Condensations , stereocontrol , Olefination
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
